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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS15
All Species:
17.88
Human Site:
S445
Identified Species:
43.7
UniProt:
Q8TE58
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE58
NP_620686.1
950
103287
S445
P
G
A
S
Y
T
L
S
Q
Q
C
E
L
A
F
Chimpanzee
Pan troglodytes
XP_522253
950
103283
S445
P
G
A
S
Y
T
L
S
Q
Q
C
E
L
A
F
Rhesus Macaque
Macaca mulatta
XP_001113698
950
103442
S445
P
G
A
S
Y
T
L
S
Q
Q
C
E
L
A
F
Dog
Lupus familis
XP_546393
936
100397
S445
P
G
A
S
Y
T
L
S
Q
Q
C
E
L
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P59384
950
103919
S445
P
G
T
S
Y
S
L
S
Q
Q
C
E
L
A
F
Rat
Rattus norvegicus
Q9WUQ1
967
105687
N485
P
G
T
L
Y
D
A
N
R
Q
C
Q
F
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417874
931
100868
N424
P
G
T
S
Y
S
L
N
Q
Q
C
E
L
A
F
Frog
Xenopus laevis
NP_001088627
928
102191
N435
P
G
T
L
Y
D
A
N
K
Q
C
Q
F
T
F
Zebra Danio
Brachydanio rerio
NP_001119901
958
105214
E439
P
G
A
S
Y
G
L
E
R
Q
C
E
L
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
H515
P
G
K
K
Y
D
A
H
Q
Q
C
K
F
V
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
80.6
N.A.
93
47.9
N.A.
N.A.
76
49
62.2
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
99.6
99.1
85.2
N.A.
95.3
65.3
N.A.
N.A.
83.6
66.9
77.5
N.A.
N.A.
N.A.
28.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
40
N.A.
N.A.
80
40
80
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
60
N.A.
N.A.
93.3
60
86.6
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
30
0
0
0
0
0
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% C
% Asp:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
70
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
100
% F
% Gly:
0
100
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
10
0
0
10
0
0
0
% K
% Leu:
0
0
0
20
0
0
70
0
0
0
0
0
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
70
100
0
20
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
0
0
70
0
20
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
40
0
0
40
0
0
0
0
0
0
0
20
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _